• Shanmugam Karthikeyan
• Samuelraj Isaiah
• Geetha G.N

Study performed to access the irritation potential of marketed permanent hair colourant contains para-phenylenediamine (PPD) and ammonia as per the OECD Guidelines. The test item was applied to New Zealand white rabbit skin and covered with a gauze patch, which was held in place with non-irritating tape. The clinical signs of toxicity, mortality, body weight change and skin reactions of erythema and oedema were evaluated at various intervals of time (1 hr, 24 hr, 48 hr and 72 hr). The test material produced a primary irritation index of 0.3 and was classified as “Mild Irritant”. No corrosive effects were noted.

Assessment on Dermal Irritation Potential of Permanent Hair Colour with para-Phenylenediamine (PPD)

"Assessment on Dermal Irritation Potential of Permanent Hair Colour with para-Phenylenediamine (PPD)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 7, page no.575-580, July-2018, Available :http://www.jetir.org/papers/JETIR1807090.pdf

"Assessment on Dermal Irritation Potential of Permanent Hair Colour with para-Phenylenediamine (PPD)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 7, page no. pp575-580, July-2018, Available at : http://www.jetir.org/papers/JETIR1807090.pdf