• Dr CHANDRA KANT BHARDWAJ
• Dr Anjna Kumari

Abstract In the present study, Mn(II) and Ni(II) complexes have been prepared by reacting metal Nitrate with the ligand (Alprazolam), which have the general structural composition [(L) M(NO3)2], where M=Mn(II) and Ni(II) and L=Alprazolam [8-chloro-1-methyl-6-phenyl-4H-1,2,4-trizolo (4,3-a) (1,4) benzodiazepine].The complexes were characterised on the basis of elemental analysis, molecular weight and IR data. The shift in the characteristic infrared frequencies of the free ligand bands confirm the coordination. The IR data of the complexes reveal the bidentate nature with [N(1) and N(4)] sites of the ligand. All the complexes, ligand and metal salts have been screened for antibacterial and antifungal activities against selected microbes. Biocidal studies show that the Ni(II) complexes is more effective than Mn(II) complexes.

Metal complexes, Alprazolam and Biocidal study.

"Synthesis, Characterisation and Biological Studies of Mn(II) and Ni(II) complexes with Drug Alprazolam [8-Chloro-1-mthyl-6-phenyl-4H-1,2,4-triazolo (4,3-a) (1,4) benzodiazepine]", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 7, page no.703-707, July-2018, Available :http://www.jetir.org/papers/JETIR1807458.pdf

"Synthesis, Characterisation and Biological Studies of Mn(II) and Ni(II) complexes with Drug Alprazolam [8-Chloro-1-mthyl-6-phenyl-4H-1,2,4-triazolo (4,3-a) (1,4) benzodiazepine]", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 7, page no. pp703-707, July-2018, Available at : http://www.jetir.org/papers/JETIR1807458.pdf