• Dr. G.Gnanarajan
• Gurleen Kaur
• Preeti Kothiyal

In the current research, Montelukast oral jelly was formulated. The objective behind the research was to develop Montelukast oral jelly using taste masking abilities especially for paediatric patients for the treatment of allergic conditions like hay fever or seasonal allergic rhinitis and asthma. The unique feature of oral jelly is that it is easily chewed and dissolves in saliva and hence doesn’t require water. Moreover, Jellies are formed by aggregation of polymers with minimum two components; the gelling agent and the fluid component. Different batches were prepared using different concentrations of gellan gum (1%, 2%, 3% and 4%) and gelatine (1%, 1.5%, 2% and 2.5%) and prepared by the heating method. The prepared jelly was evaluated for the various parameters like appearance, pH, viscosity, texture, sugar crystallization, stiffness and invitro release study. The pH was found in the range of 6.9 ± 0.503 to 7 ± 0.404, viscosity increases with the increase in concentration of gelling agent, the prepared batches were non-sticky. invitro drug release study was performed by using simulated salivary fluid and percentage of drug release of formulation was found to be 58.52 to 92.08%. These parameters show satisfactory results therefore, the research opened new doors for bitter drugs.

oral route, oral jellies, montelukast sodium, paediatrics

"FORMULATION AND EVALUATION OF MONTELUKAST SODIUM ORAL JELLY FOR PEDIATRICS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 7, page no.448-460, July-2018, Available :http://www.jetir.org/papers/JETIR1807529.pdf

"FORMULATION AND EVALUATION OF MONTELUKAST SODIUM ORAL JELLY FOR PEDIATRICS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 7, page no. pp448-460, July-2018, Available at : http://www.jetir.org/papers/JETIR1807529.pdf