UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 5 Issue 7
July-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1807790


Registration ID:
185539

Page Number

468-474

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Title

ANTIMYCOBACTERIAL ACTIVITY OF SULFONE DERIVATIVES BY LUCIFERASE REPORTER PHAGE (LRP) ASSAY

Abstract

Schiff bases of N,N'-(sulfonylbis(4,1-phenylene))bis(1,1-diphenylmethanimine) and N,N'-(sulfonylbis(4,1-phenylene))bis(propan-2-imine) obtained by the condensation of sulfone and ketones with 1:2 ratio have been synthesized and characterized by spectroscopic studies viz., Fourier-transform infrared, proton Nuclear Magnetic Resonance and Ultraviolet-visible. The synthesized compounds antimycobacterial activity has been against Mycobacterium tuberculosis H37Rv and clinical isolate of MTB Resistant to Isoniazid (H) and Rifampicin (R) and the results suggested that both derived compounds have significant antimycobacterial activity.

Key Words

antimycobacterial assay, Mycobacterium tuberculosis (H37Rv), Isoniazid (H), Rifampicin (R) and relative light units

Cite This Article

"ANTIMYCOBACTERIAL ACTIVITY OF SULFONE DERIVATIVES BY LUCIFERASE REPORTER PHAGE (LRP) ASSAY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 7, page no.468-474, July-2018, Available :http://www.jetir.org/papers/JETIR1807790.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"ANTIMYCOBACTERIAL ACTIVITY OF SULFONE DERIVATIVES BY LUCIFERASE REPORTER PHAGE (LRP) ASSAY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 7, page no. pp468-474, July-2018, Available at : http://www.jetir.org/papers/JETIR1807790.pdf

Publication Details

Published Paper ID: JETIR1807790
Registration ID: 185539
Published In: Volume 5 | Issue 7 | Year July-2018
DOI (Digital Object Identifier):
Page No: 468-474
Country: Tiruchirappalli., Tamilnadu, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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