• Pushpa
• J.S.Biradar

A series of new1-(1-(3-phenylpropyl)-1H-indol-3-yl)-methanamines were synthesised by reductive amination of 1-(3-phenylpropyl)-1H-indole-3-carbaldehyde and primary amines using NaBH4 as reducing agent. The higher amines were then subjected to Schotten Baumann reaction to obtain tertiary amides. The chemical structures of synthesized compounds were confirmed by IR, 1H NMR and Mass spectroscopic and elemental data. These compounds were also screened for their in vitro antimicrobial activity by cup plate method using Ciprofloxacin and Amphotericin B as standards against gram positive and gram negative bacteria and fungi respectively and antioxidant activity by DPPH method

Indole-3-carboxaldehyde, Thiophene, Pyridine, antimicrobial and antioxidant activity.

"Facile Synthesis and Antimicrobial Activity Of Novel N,N-Dialkyl-(1H-Indol-3-yl)methyl aryl amides", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 9, page no.823-835, September-2018, Available :http://www.jetir.org/papers/JETIR1809630.pdf

"Facile Synthesis and Antimicrobial Activity Of Novel N,N-Dialkyl-(1H-Indol-3-yl)methyl aryl amides", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 9, page no. pp823-835, September-2018, Available at : http://www.jetir.org/papers/JETIR1809630.pdf