• Shanmugam Karthikeyan
• Samuelraj Isaiah

The evaluation of eye irritation potential is essential to ensuring the safety of individuals in contact with wide range of substances designed for industrial, pharmaceutical or cosmetic use. The present paper is an attempt to investigate the eye irritation potential of marketed permanent hair colour contains para-phenylenediamine (PPD) and ammonia as per the OECD guideline 405 (Organization for Economic Cooperation and Development). The clinical signs of body weight and ocular reaction (Cornea, Chemosis, Conjunctivae and Iris) were recorded at various intervals of time such as 1, 24, 48, and 72 hours post instillation. Test material produced no clinical signs of toxicity and mortalities noticed during the study. In the both initial and confirmatory test, eye irritation was observed. The permanent hair colour classified as an “Irritant” (Category 2B).

Evaluation on Ocular Irritation Potential of Marketed Permanent Hair Colour

"Evaluation on Ocular Irritation Potential of Marketed Permanent Hair Colour", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 11, page no.319-324, November-2018, Available :http://www.jetir.org/papers/JETIR1811549.pdf

"Evaluation on Ocular Irritation Potential of Marketed Permanent Hair Colour", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 11, page no. pp319-324, November-2018, Available at : http://www.jetir.org/papers/JETIR1811549.pdf