• SATHISH KUMAR D

Abstract An antimicrobial efficiency of leaves and stem parts of Andrographis echioides (L.) nees were studied by using seven different solvent extracts tested against four human pathogenic bacteria such as Staphylococcus aureus, Bacillus cereus, Serratia marcescens and Klebsiella pneumoniea. Fungal pathogens like Candida albicans and Aspergillus niger. Both leaves and stem extract exhibited significant activity against selected human pathogens. The ethanol, methanol, acetone, ethyl acetate extracts showed highest zone of inhibition against the entire tested microorganism. The lowest activity observed on chloroform extract. No zone of inhibition determined on petroleum ether and aqueous plant extracts except Staphylococcus aureus lowest zone was founded. Completely no activity found in all the solvent extracts against Aspergillus niger. The results approve that A. echioides can be used as a source of medicine to fight infection affected by susceptible bacteria and fungi.

Key words - Antimicrobial activity, Disc diffusion assay, Human pathogens and Medicinal plant Introduction

"Antimicrobial activity of leaves and stem extracts of Andrographis echioides (L.) Nees.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 11, page no.275-282, November-2018, Available :http://www.jetir.org/papers/JETIR1811738.pdf

"Antimicrobial activity of leaves and stem extracts of Andrographis echioides (L.) Nees.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 11, page no. pp275-282, November-2018, Available at : http://www.jetir.org/papers/JETIR1811738.pdf