• Sharad kumar Tripathi
• Ravikant Singh
• Saket Jha
• Anand Pandey
• Anupam Dikshit

This study was focused on the comparison of biological activities of the leaf extracts of Eclipta alba L., against Klebsiella pneumoniea (MTCC-4032). The extracts were prepared from the leaves of the aforementioned plant species using Rotavapour R-300. The antibacterial activity of the extracted essential oils was evaluated against Klebsiella pneumoniea (MTCC-4032) using broth micro-dilution method recommended by Clinical Laboratory Standards Institute (CLSI). The Inhibition Concentration i.e. IC50 and Minimum Inhibition concentrations (MIC) using SpectramaxPlus384 Molecular Devices were recorded. The IC50 value of acetone leaf extract, ethanol leaf extract and petroleum ether extract were showed 0.020, 0.080 and 0.039 mg/ml respectively. The acetone leaf extract was found to be most effective with their MIC 0.020 mg/m1 whereas ethanol leaf extract was found to be least effective with their MIC 1.030 mg/ml against K. pneumoniea. Hence, leaf extracts of aforementioned plant exhibit great potential for the development of eco-friendly, non-toxic, cost effective, anti-bacterial formulations.

Antibacterial activity, E. alba, Broth Micro-dilution

"Comparison of Antibacterial Activities of Leaf extracts of Eclipta alba against Klebsiella pneumoniea", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 11, page no.349-352, November-2018, Available :http://www.jetir.org/papers/JETIR1811854.pdf

"Comparison of Antibacterial Activities of Leaf extracts of Eclipta alba against Klebsiella pneumoniea", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 11, page no. pp349-352, November-2018, Available at : http://www.jetir.org/papers/JETIR1811854.pdf