• V.A.J.Huxley

Apoptosis, the programmed cell death regulates various functions of an organisms. If it plunge their regulation the cell become tumor/ Cancer. Apoptosis induction is one of the new methods of cancer treat. Lot of commercial apoptotic regulating drug are available in the market and they are used very little amount because of their deprived effects and cost. Now lot of plants and natural products were screened for their apoptotic regulating efficiency. In the present study, the apoptotic regulating efficiency of three marine sponge extracts collected from south peninsular coast were screened with standard protocols. Among that the methanolic extracts of sponge Sigmodoicia proven their significant activity over the other two tested sponge extracts through its cytotoxicity, Hydrogen peroxide scavenging, DPPH scavenging assays. More over that the same extract produced effective DNA degradation than other two tested sponge extracts

Apoptosis, DPPH assay, MTT assay, Hydrogen peroxide scavenging assay

"Apoptosis Regulating Efficacy of Chosen Indian South Peninsular Coast Marine Sponge Extracts", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.428-434, December-2018, Available :http://www.jetir.org/papers/JETIR1812362.pdf

"Apoptosis Regulating Efficacy of Chosen Indian South Peninsular Coast Marine Sponge Extracts", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp428-434, December-2018, Available at : http://www.jetir.org/papers/JETIR1812362.pdf