• Bajivali Shaik
• Dr. Mohan Seelam
• Dr. Prasada Rao Kammela
• Abdul Mathin Shaik
• Subba Rao Yarlagadda

An accurate, rapid, economical and simple, reliable assay method was developed and validated for the simultaneous estimation of Oxymetazoline HCl and Sorbitol using RP-HPLC. In the proposed method efficient chromatographic separation was achieved using waters X-Bridge C8 column (150mm x 2.1mm 3.5um) as a stationary phase and Acetonitrile: 0.1% TEA in water adjust pH=2.5 with OPA (40:60 v/v) as a mobile phase with a flow rate of 1ml/min and UV-detection at 261nm.Chromatography was carried out isocratically at ambient temperature and the run time was approximately 7min.

Oxymetazoline HCl and Sorbitol, HPLC

"Analytical Stability Indicating HPLC Assay and Validation of Oxymetazoline HCl and Sorbitol in Bulk and Pharmaceutical Dosage form", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.653-659, December-2018, Available :http://www.jetir.org/papers/JETIR1812597.pdf

"Analytical Stability Indicating HPLC Assay and Validation of Oxymetazoline HCl and Sorbitol in Bulk and Pharmaceutical Dosage form", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp653-659, December-2018, Available at : http://www.jetir.org/papers/JETIR1812597.pdf