• Kanmani K
• Sankareswaran M
• Anbalagan S
• Moorthy M
• Michael A

Indian Poultry industry contributes a major role in the economy through the food processing sector. Pathogens’ causing the diseases in poultry leads to significant losses in poultry industry. Campylobacteriosis is a zoonotic infection caused by Campylobacter jejuni colonizes the gastrointestinal tracts of a wide range of wild and domestic animals. Chickens are widely recognized as the main source of human exposure to Campylobacter jejuni infections. Campylobacter associated diarrhoea in patients have been suggested to be linked to the consumption of meat which leads to Guillain Barre´syndrome, diarrhoea, and other intestinal infections. The use of antibiotics to eliminate or to prevent Campylobacter jejuni infection is not recommended for various reasons. Chicken egg yolk antibody (IgY) was raised against Campylobacter jejuni by immunizing the whole cell antigen prepared from the isolates obtained from the chicken intestine. The specific activity of the purified IgY shows highest titre, determined by ELISA. IgY activity while treated with different sugars like sucrose, lactose and dextran and its stability was evaluated under different conditions. IgY was stable at 60-70ᵒC in the presence of sugars at pH 5-7. Thus the specific IgY has the ability to survive in the gastrointestinal tract and its binding activity to the bacterial cells helps to decrease the growth rate that provides passive protection against Campylobacter jejuni infections in Chickens.

Poultry, Intestinal infections, IgY, ELISA, Stability

"Generation and Passive protection of Chicken Egg Yolk antibodies (IgY) against Campylobacter jejuni ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.420-431, December-2018, Available :http://www.jetir.org/papers/JETIR1812754.pdf

"Generation and Passive protection of Chicken Egg Yolk antibodies (IgY) against Campylobacter jejuni ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp420-431, December-2018, Available at : http://www.jetir.org/papers/JETIR1812754.pdf