• S.Selvakumar
• S. Shankar

Objectives: Mushroom β-glucan has the ability to affect many cellular functions, including cellular glucose uptake. Although cumulative evidence in literature suggests a connection between β-glucan and reduction of blood glucose concentration, a mechanism of how β-glucan affects cellular glucose uptake has not been demonstrated. Methods: A set of spectroscopic, chemical and separation methods are used for this purpose. Among them, NMR spectroscopy is known as a powerful tool in structural analysis of glucans both in solution and in solid state. Results: In this study, β glucan isoalated from Agrocybe cylindracea, characterized by 1H NMR, 13C NMR spectroscopy and the invitro antidiabetic effect of β-glucan by the α-amylase inhibitory activity also analyzed. Conclusions: The highest inhibitory activity (75.82%) was detected at 2.0 mg/mL. This result indicated that β-glucan possessed higher inhibitory activitiy against α-Amylase.

β-glucan, Agrocybe cylindracea , invitro antidiabetic, antimicrobial

"ISOLATION, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF β-GLUCAN ISOLATED FROM EDIBLE MUSHROOM Agrocybe cylindracea", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.636-645, December-2018, Available :http://www.jetir.org/papers/JETIR1812783.pdf

"ISOLATION, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF β-GLUCAN ISOLATED FROM EDIBLE MUSHROOM Agrocybe cylindracea", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp636-645, December-2018, Available at : http://www.jetir.org/papers/JETIR1812783.pdf