• Rishabha Malviya

The ineffectiveness of existing antibiotics inculcates the search of novel metabolites from specific ecosystems. Microbial ecosystem specially, actinomycetes a fungi like bacteria consist an extensive and diverse species with an unparalleled ability to produce diverse secondary metabolites high frequently studied by researchers. These bacteria have been studied extensively by the pharmaceutical industry and account for a disproportionately large amount of the $25.3 billion annual global sale. According to the data 2007, the contribution of biologically occurring chemicals in drug development. The actinomycetes products have a tremendous success for the past few decades. Universally Actinomycetes are acknowledged as a vital player in the drug discovery process. Actinomycetes are highly significant in drug discovery and development due to its high G+C content. Among the bioactive compounds, nearly 45 percentage produced by actinomycetes, 35 % by fungi and 20 % by unicellular eubacteria. Apart from infectious disease, Actinomycetes are also reported to produce many industrially and medically important enzymes. Acarbose is an oral alpha-glucosidase and alpha-amylase inhibitor for the oral treatment of type II diabetes mellitus is isolated from actinomycetes. Thus actinomycetes are potent secondary metabolite producer and biotechnologically interesting organism need to explore much. By this review, we explore and update our knowledge on the potential of actinomycetes and their bio-discovery potential.

Streptomyces, Micromonospora, myeloma, Natamycin, Diabetes

"Review on Pharmaceutical Products from Actinomycetes", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.1211-1217, June-2021, Available :http://www.jetir.org/papers/JETIR1812D74.pdf

"Review on Pharmaceutical Products from Actinomycetes", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp1211-1217, June-2021, Available at : http://www.jetir.org/papers/JETIR1812D74.pdf