• DESSY V J
• DR.S.R.SIVAKUMAR

ABSTRACT The in vitro techniques and the biological investigations of microbiological and the phytochemical tests, which includes antimicrobial and thrombolytic study of SCF extract of Curcuma aeruginosa. This plant is used in the traditional medicinal system for cure of a variety of diseases. The plant has a characteristic rhizome of bluish‑black color with pungent smell and hot bitter taste. The rhizome is traditionally used in the treatment of hemorrhoids, leprosy, asthma, cancer, fever, wounds, vomiting, menstrual disorder, anthelmintic, aphrodisiac, gonorrheal discharges, and inflammation. Furthermore, the smooth muscle relaxant, anti‑tumour and anti‑oxidant properties of C. caesia rhizome extract had been reported. Due to its high medicinal value, the plant is in great demand in central India. The SCF extract of the plant possess thrombolytic activity, along with streptokinase as a positive control and water as a negative control. Using an in vitro thrombolytic model the extract showed (77.11±2.13%) thrombolytic activity. Through this study it was found that it possesses thrombolytic properties that could lyses blood clots in vitro. The antibacterial activity was determined by using the agar diffusion method. The extract of the plant showed moderate activity against Gram-positive bacteria Bacillus subtilis (13.7±1.53) and gram-negative bacteria Klebsiella pneumoniae (13.3±1.15). The concentration of the extracted sample was 2mg/20µl was used for antibacterial activity.

streptokinase, Thrombolytic activity, SCF extract, antibacterial activity.

"Thrombolytic activity and Antimicrobial properties of SCF extract of Curcuma aeruginosaRoxb", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.166-176, February-2019, Available :http://www.jetir.org/papers/JETIR1902022.pdf

"Thrombolytic activity and Antimicrobial properties of SCF extract of Curcuma aeruginosaRoxb", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp166-176, February-2019, Available at : http://www.jetir.org/papers/JETIR1902022.pdf