• Priyanka sharma
• Gajanand modi

In developing countries of tropical regions skin diseases are more common due to mycotic infection. In many parts of the world the use of medicinal herbs in the treatment of skin diseases including mycotic infections is an age-old practice. The drugs which are being used against dermatophytosis exhibits several side effects and have limited efficacy. In this study, the in-vitro antifungal activity of Calotropis procera leaves extract in different solvents (petroleum ether, chloroform, ethyl acetate and ethyl alcohol and aqueous) were evaluated against two different genera of dermatophytes viz. Trichophyton rubrum and Epidermophyton floccosum by disc diffusion and broth dilution methods. The results revealed that ethyl acetate is the best extractive solvent for antifungal properties. The minimum inhibitory concentration (MIC) for ethyl acetate extract was also observed. The MIC values of this compound was 8 mg/ml. Present study concludes that leaves of C. procera demonstrated strong inhibitory effect on the test organisms and established a good support for the use of this plant as a new source of developing local antifungal agents. However, further studies are needed to determine the efficacy of active component of this extract.

Calotropis procera, Antifungal activity, disc diffusion method, minimum inhibitory concentration

"EVALUATION OF ANTIFUNGAL ACTIVITY OF CALOTROPIS PROCERA LEAF EXTRACT: AN IN VITRO STUDY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.161-167, February-2019, Available :http://www.jetir.org/papers/JETIR1902327.pdf

"EVALUATION OF ANTIFUNGAL ACTIVITY OF CALOTROPIS PROCERA LEAF EXTRACT: AN IN VITRO STUDY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp161-167, February-2019, Available at : http://www.jetir.org/papers/JETIR1902327.pdf