• PILTY PETER A
• JISMINE MATHEW

Abstract Hedychium coronarium, the member of family of Zingibereaceae is a must-have plant in medicinal herb garden. It is reported that it contains phenols, terpenoids etc. The aim of this study was to evaluate the cytotoxic and genotoxic effects of rhizome extract of Hedychium coronarium on the Allium cepa cell cycle. Cells of root tips of Allium cepa were used as an in vivo test system for monitoring the genotoxicity of this medicinal plant. The slides were prepared by the squashing technique, scoring 12000 cells for each group of bulbs. The mitotic index (MI) was calculated and then a statistical analysis was performed using analysis of variance.. The results showed that rhizome extract caused a reduction of MI compared to control. The antiproliferative effect of rhizome extracts increased with a long duration . Mitotic anomalies keep on decreasing with increasing duration. •

Keywords : Allium cepa , Hedychium coronarium, Genotoxicity,

"EVALUATION OF THE CYTOTOXICITY AND GENOTOXICITY OF RHIZOME EXTRACT OF HEDYCHIUM CORONARIUM USING THE ALLIUM TEST", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.267-273, February-2019, Available :http://www.jetir.org/papers/JETIR1902347.pdf

"EVALUATION OF THE CYTOTOXICITY AND GENOTOXICITY OF RHIZOME EXTRACT OF HEDYCHIUM CORONARIUM USING THE ALLIUM TEST", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp267-273, February-2019, Available at : http://www.jetir.org/papers/JETIR1902347.pdf