• Dr. Devaraju
• Dhondiba Vishwanath1
• Dr.Ranjini.p
• Dr, Y,B Basavaraju

Abstract: Lignans are naturally occurring class of secondary metabolites in plant kingdom that have numerous biological effects in mammals. These compounds contains tetralone moiety, besides of this, the triazoles are the special class of heterocyclic compounds with a broad spectrum of biological activities. Therefore we synthesized triazole derivatives of substituted -9-(3, 4, 5-trimethoxyphenyl) tetralone in presence of Zn catalyst in THF in good yields by chalcone method. All synthesized compounds were characterized by spectral techniques. Further, the compounds were evaluated for microbial activity.

Lignans, tetralone, triazole, zinc, azide, Click, Simmon-smith, azide

"SYNTHESIS AND CHARACTERISATION OF SUBSTITUTED -9-(3, 4, 5-TRIMETHOXYPHENYL) TETRALONE-TRIAZOLES BY CHALCONE PATH AND THEIR BIOLOGICAL ACTIVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.637-645, February-2019, Available :http://www.jetir.org/papers/JETIR1902787.pdf

"SYNTHESIS AND CHARACTERISATION OF SUBSTITUTED -9-(3, 4, 5-TRIMETHOXYPHENYL) TETRALONE-TRIAZOLES BY CHALCONE PATH AND THEIR BIOLOGICAL ACTIVITY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp637-645, February-2019, Available at : http://www.jetir.org/papers/JETIR1902787.pdf