• Amudha M
• Manikandan R
• Sharmila banu

The determination of the antioxidant and anti–inflammatory activity of selected medicinal plant namely Coccinia grandis has been studied using different solvents of aqueous, and methanol extracts. Invitro antioxidant potential of fruit of Coccinia grandis with three different methods like hydrogen peroxide scavenging (H2O2) assay, reducing power assay and thiobarbataric acid assay were evaluated. Determination of antioxidant and anti - inflammatory activity of different concentration 0.2, 0.4, 0.6, 0.8 and 1.0 and standard (Diclofenac sodium) of plant extract. Among the three methods, the antioxidant activity for more suitable in Thiobarbataric acid activity than the other methods. The aqueous, and methanol extract of excellent percentage of activity hydrogen peroxide scavenging (H2O2) assay when low concentration of aqueous extract also moderate percentage of activity from reducing power assay were observed in the anti – inflammatory activity of Coccinia grandis fruit extract of higher concentration was extraordinary performance observed. These observations confirm that methanolic extract of different polyphenolic constituents and its importance in antioxidant and anti - inflammatory activity were performed.

Anti oxidant and anti – inflammatory activity, Coccinia grandis fruit.

"INVITRO ANTIOXIDANT AND ANTI – INFLAMMATORY ACTIVITY OF Coccinia grandis L.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.2-8, February-2019, Available :http://www.jetir.org/papers/JETIR1902A01.pdf

"INVITRO ANTIOXIDANT AND ANTI – INFLAMMATORY ACTIVITY OF Coccinia grandis L.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp2-8, February-2019, Available at : http://www.jetir.org/papers/JETIR1902A01.pdf