UGC Approved Journal no 63975(19)
New UGC Peer-Reviewed Rules

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 6 Issue 2
February-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1902B74


Registration ID:
198366

Page Number

505-526

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Title

Squalene, Biosynthesis and its role in production of bioactive compounds, a Proper Scientific Challenge – A Review

Abstract

Squalene is an isoprenoids unit of polyunsaturated hydrocarbon, naturally present in all plant sources. An emphasis has been placed upon the intensive investigations on account of its various potential therapeutic activities. It is an intermediate metabolite or precursor for bioactive compounds like cholesterol, sterol, hapanoid, hormones, vitamins and triterpenoids in various organisms from prokaryotes to eukaryotes. It is present in large quantities in liver oil of shark but it is considerably present in various plants - derived oil; such as olive oil, palm oil, wheat-germ oil, amaranth oil and rice bran oil. Squalene is used to treat variety of cancers and to reduce blood cholesterol and triglyceride levels in the blood. Due to its increasing roles in cosmetic, nutroceutics, pharmaceutical and automobile industries, the demand for this compound is high. Squalene is structurally related to β-carotene, coenzyme Q10 (Ubiquinone) , vitamins A, E and K. In this review, we accounted its occurrence, structure, physical and chemical properties, and its biological significance in food, human health, cosmetic and pharmaceutics. In addition, its biosynthesis and its role as a precursor for many bioactive compounds also discussed.

Key Words

Biosynthesis, Metabolite, Precursor, Squalene, Triterpenoid

Cite This Article

"Squalene, Biosynthesis and its role in production of bioactive compounds, a Proper Scientific Challenge – A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.505-526, February-2019, Available :http://www.jetir.org/papers/JETIR1902B74.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Squalene, Biosynthesis and its role in production of bioactive compounds, a Proper Scientific Challenge – A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp505-526, February-2019, Available at : http://www.jetir.org/papers/JETIR1902B74.pdf

Publication Details

Published Paper ID: JETIR1902B74
Registration ID: 198366
Published In: Volume 6 | Issue 2 | Year February-2019
DOI (Digital Object Identifier):
Page No: 505-526
Country: Tiruchirappalli, Tamil Nadu, India .
Area: Biological Science
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIR1902B74
Published Paper PDF: https://www.jetir.org/papers/JETIR1902B74

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