• A. Palanivel
• Gunasekaran
• M. Prakash

Fish have often been called the poor man’s source of animal protein. The systematic use of fish concentrate has long proven advantageous in animal husbandry and there is growing recognition of its potential for improving human nutrition and health. Channa striatus, or snakehead murrel, is an obligate air-breathing freshwater fish which inhabits all types of water bodies. C. striatus is commonly consumed as a food fish. C. striatus is recorded as high medicinal properties containing fish. The popularity of C. striatus as a therapeutic agent is known to folk medicine in its efficacy in treating wounds, relieving pain and boosting energy in the sick and elderly. Hence in the present study effort has been made to study the antitumour and antioxidant activity of the acid soluble collagen isolated from the freshwater snakehead fish Channa striatus. The acid soluble collagen extracted freshwater snakehead fish was tested against cancer cells (human colon cancer (HT-29) and human breast adenocarcinoma) at different concentrations. Similarly the free radical scavenging capability was also tested for the acid soluble collagen. The result revealed that the acid soluble collagen extracted from freshwater snakehead fish C. striatus exerts both antioxidant and anticancer activity. Whereas at lower concentration the acid soluble collagen has not much effect on the normal Vero cell line having 95 % cell viability which shows a new way for using as medicine against cancer.

Channa striatus, antioxidant, antitumour, fish collagen

"Antioxidant and antitumour activity of acid soluble collagen extracted from freshwater snakehead fish Channa striatus", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.411-431, February-2019, Available :http://www.jetir.org/papers/JETIR1902C64.pdf

"Antioxidant and antitumour activity of acid soluble collagen extracted from freshwater snakehead fish Channa striatus", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp411-431, February-2019, Available at : http://www.jetir.org/papers/JETIR1902C64.pdf