• Raosaheb S Shendge
• Kishor S Salunkhe

Oral organization of various measurements structures is the most widely recognized type of organization because of more prominent patient consistence and adaptability. Directed drug conveyance framework is the framework in which the measurements structure is altered to convey the drug at the objective district or at the infection area. In colon focused on drug conveyance framework the drug is focused to the colon. The colon focused on drug conveyance framework is utilized for the therapy of different sicknesses identified with colon like incendiary entrail infection, crohn's illness, colon malignancy, and so forth. This focusing of drug to the illness site brings down the prerequisite of higher portions of drug hence decreasing the dose recurrence and cost of the drugs. Colon focused on drug conveyance framework will likewise bring down the foundational results. This survey article analyzes the various ways to deal with colon focused on drug conveyance like pH and time subordinate, prodrug, microbial set off drug conveyance, azo hydrogels, pressure controlled drug conveyance, pulsatile drug conveyance framework, osmotic controlled drug conveyance framework, and so on The microbial set off drug conveyance framework depends on the chemicals delivered by various microflora in the colon. Of the various methodologies the new methodologies like weight controlled, osmotic controlled drug conveyance frameworks are profoundly powerful.

colon targeted drug delivery, prodrug, osmotic pressure, microflora, pH sensitivity, time dependence, nanoparticles

"FORMULATION AND INVITRO EVALUATION OF COLON TARGETEDMATRIX TABLETS OF IBUPROFEN", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.1314-1321, February-2019, Available :http://www.jetir.org/papers/JETIR1902D87.pdf

"FORMULATION AND INVITRO EVALUATION OF COLON TARGETEDMATRIX TABLETS OF IBUPROFEN", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp1314-1321, February-2019, Available at : http://www.jetir.org/papers/JETIR1902D87.pdf