• Mohammed Sayeed
• Dr.SHANMUGAPANDIYAN.P

Neurons are the design squares of the tangible sensory network which fuses the cerebrum and the spinal cord. Depression is the second most common psychiatric ailment, affecting 21 percent of the worldwide people. The age range is rapidly shrinking, from 40-50 years old to 25-35 years old, as seen around the world. Morus alba, also called as white mulberry, is a quickly developing, little to average-sized mulberry tree. Moranoline, albafuran, albanol, morusin, kuwanol, calystegin and hydroxymoricin are confined to various biochemical mixtures from mulberry plants that assume a significant role in the drug industry. The purpose of the current review was to evaluate the neuropharmacological effect of hydroethanolic lef extract of Morus alba by using various behavioral models of rodent animals. The observation suggests that the phenolic intensification present in the concentrate could be responsible for the rummaging effect of nitric oxide. The high antioxidant activity of the HEMA may because of their phenolic constituents. Anxiolytic capability of HEMA at 200 and 400 mg/kg was practically significant to that of diazepam as indicated by elevated plus maze model. Tail suspension models were utilized for the assessment of anxiolytic action of HEMA. Results reported that 200 and 400 mg/kg dosage of HEMA indicated potent antidepressant effect that was like that of imipramine. Furthermore, the outcomes of photoactometer test affirm considerable antidepressant capability of HEMA. The sedative properties of Morus alba Linn leaves might be relevant to its future therapeutic application.

Morus alba, antioxidants, toxicity, elevated plus maze, photoactometer.

"Neuropharmacological Profile of Hydroethanolic Extracts of Leaves of Morus alba Linn in Animal Model", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.1903-1910, February-2019, Available :http://www.jetir.org/papers/JETIR1902E67.pdf

"Neuropharmacological Profile of Hydroethanolic Extracts of Leaves of Morus alba Linn in Animal Model", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp1903-1910, February-2019, Available at : http://www.jetir.org/papers/JETIR1902E67.pdf