• Pallavi Rain
• Jyoti Batra
• Satish Kumar
• Manjari Rain

Critical illness is a life-threatening condition in which if medical intervention is lacking it can result in mortality. Critical illness can be acute or chronic and it's generally seen after an initial insult to the body which can be trauma, surgery, cancer, or sepsis. To support critically ill patients, intensive care unit has been established in hospitals. In most of the critically ill patients, ventilatory support is essential for survival besides this trained clinician plays an important role by cataloguing the vital signs accurately and recognizing the abnormal values and deciding appropriate treatment accordingly. Sepsis is a common outcome in critically ill patients and it is also the most common cause of the increase in mortality in these patients. In sepsis, dysfunction of the organ develops which is because of the imperfectly regulated host response to infection, and due to that overdrive of the immune system response, this is a life-threatening condition. Sepsis can lead to severe sepsis which leads to septic shock if proper and timely treatment is not provided. Septic shock is a very severe form of sepsis in which body blood pressure drops to alarmingly low levels after an infection which is a potentially fatal condition. Therefore, it is essential to recognize sepsis in the early stages by interpreting appropriate biomarkers, which guides to easy management and proper treatment protocol can be set for critically ill patients in the intensive care unit. This review paper gives a brief account of critical illness and its association with sepsis and its management.

Critical illness, sepsis, septicaemia

"Critical illness and its association with sepsis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.152-175, February-2019, Available :http://www.jetir.org/papers/JETIR1902F01.pdf

"Critical illness and its association with sepsis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp152-175, February-2019, Available at : http://www.jetir.org/papers/JETIR1902F01.pdf