• Dr.P.lakshmaiah
• B. Hima saisree
• Ch.Siva sai
• L.Deepthi
• B.Sridevi

Parkinson’s disease affects the nerve cells in the brain that produce dopamine. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. The disorder that affects predominately dopamine-producing ‘dopaminergic’neurons in a specific area of the brain called substantial nigra. Symptoms generally develop slowly over years. The progression of symptoms is often a bit different from one person to another due to the diversity of the disease. People with Parkinson’s may experience tremor mainly at rest and described as pill rolling tremor in hands. Other forms of tremor are possible like Bradykinesia, Limb rigidity, Gait and balance problems. Prevalence rates of depressive disorders in Parkinson’s disease (Parkinson’s) vary widely across studies. Using Medline on Pub med, a systematic literature search was carried out for studies of depression in Parkinson’s disease. Some articles were included and assessed for quality. Clinically significant depressive symptoms, irrespective of the presence of a DSM (diagnostic and statistical manual) defined depressive disorder, In this study using a (semi) structured interview to establish DSM criteria, the reported prevalence of major depressive disorder was while in studies using DSM criteria without a structured interview, the reported prevalence of major depressive disorder Population studies. The report lower prevalence rates for both major depressive disorder and the clinically significant depressive symptoms than studies in other settings. This systematic review suggests that the average prevalence of major depressive disorder in Parkinson’s is substantial, but lower than generally assumed.

: DSM, Tremor, Depression, Prevalence, Dopamine, levodopa.

"A Short Review on Scales for Outcomes in Parkinson’s disease", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.180-187, March-2019, Available :http://www.jetir.org/papers/JETIR1903G29.pdf

"A Short Review on Scales for Outcomes in Parkinson’s disease", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp180-187, March-2019, Available at : http://www.jetir.org/papers/JETIR1903G29.pdf