• GEETANJALI SHARMA
• Dr.KIRTI JAIN

Abstract: Nigella sativa is one of the well known ayurvedic drug belonging to the family Liliaceae. In the present study we have investigated cytotoxic effect of plant extract of Nigella sativa using the Allium cepa root tip assay. The root of Allium cepa were exposed to different concentrations of plant extracts (50%, 100%, 150% mg/kg) for four different solvents, using distilled water as the control. Mitotic index was found to be decreasing, which was concentration dependent. All the extracts induced lowering of the mitotic index when compared to the distilled water control expect pet- ether. Keywords:Nigella sativa, cytotoxicity, Allium cepa assay, mitotic index.

Keywords:Nigella sativa, cytotoxicity, Allium cepa assay, mitotic index.

"ANALYSIS OF CYTOTOXIC POTENTIAL OF PLANT EXTRACTS OF NIGELLA SATIVA USING ALLIUM CEPA ROOT TIP ASSAY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.190-194, March-2019, Available :http://www.jetir.org/papers/JETIR1903I31.pdf

"ANALYSIS OF CYTOTOXIC POTENTIAL OF PLANT EXTRACTS OF NIGELLA SATIVA USING ALLIUM CEPA ROOT TIP ASSAY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp190-194, March-2019, Available at : http://www.jetir.org/papers/JETIR1903I31.pdf