UGC Approved Journal no 63975(19)
New UGC Peer-Reviewed Rules

ISSN: 2349-5162 | ESTD Year : 2014
Volume 12 | Issue 10 | October 2025

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Published in:

Volume 6 Issue 3
March-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1903P80


Registration ID:
569585

Page Number

621-625

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Title

Cytotoxicity and Biomedical Application Potential of Ag-ZnO Nanoparticles Synthesized from Marine Algal Extracts

Abstract

The biomedical potential of nanoparticles is closely tied to their cytotoxicity and safety profile. This study evaluates the cytotoxic and application potential of Ag–ZnO nanoparticles synthesized through green methods using Sargassum muticum (brown alga) and Gracilaria corticata (red alga). Structural characterization confirmed nanoparticle formation. Cytotoxicity was assessed using simulated MTT assays against cancer and normal cells. Results revealed dose‑dependent inhibition of cancer cell viability, with IC50 values of 42 µg/ml for Sargassum‑derived nanoparticles and 55 µg/ml for Gracilaria‑derived nanoparticles. Normal cells maintained >80% viability at 50 µg/ml, indicating relative safety. These findings highlight the potential of algal‑mediated Ag–ZnO nanoparticles in antimicrobial coatings, wound healing, and cancer therapy applications.

Key Words

Ag–ZnO nanoparticles; cytotoxicity; biomedical applications; algal extracts; cancer therapy; wound healing

Cite This Article

"Cytotoxicity and Biomedical Application Potential of Ag-ZnO Nanoparticles Synthesized from Marine Algal Extracts", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.621-625, March-2019, Available :http://www.jetir.org/papers/JETIR1903P80.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Cytotoxicity and Biomedical Application Potential of Ag-ZnO Nanoparticles Synthesized from Marine Algal Extracts", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp621-625, March-2019, Available at : http://www.jetir.org/papers/JETIR1903P80.pdf

Publication Details

Published Paper ID: JETIR1903P80
Registration ID: 569585
Published In: Volume 6 | Issue 3 | Year March-2019
DOI (Digital Object Identifier): https://doi.org/10.56975/jetir.v6i3.569585
Page No: 621-625
Country: Vizianagaram District, Andhra Pradesh, India .
Area: Physics
ISSN Number: 2349-5162
Publisher: IJ Publication


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