• Dipali Markam

Aim & objective of the study: - The main objective of this study is to evaluate the antimicrobial potential of biologically synthesized silver nanoparticles, against anaerobic bacteria Fusobacterium nucleatum. These bacteria are found in oral cavities as a part of the normal human flora and many times responsible for the oral disease like periodontitis. In this experiment silver nanoparticles were used, which are synthesized by using peel of apple. Result:-Production of Silver nanoparticles was confirmed by UV-Visible and IR spectroscopy. Particle size has determined by Zeta Potential. Antimicrobial activity has done by well diffusion method. Silver nanoparticles made by using aqueous extract of fresh apple peel shown maximum zone of inhibition of 18.25±0.500 mm at 100mg/ml against Fusobacterium nucleatum and aqueous extract of apple peel shown maximum zone of inhibition of 20.25±0.500 mm at 200mg/ml Conclusion:-The result suggested that the biogenic synthesized silver nanoparticle shown effective antimicrobial activity against F.nucleatum. Thus these particles can be utilized to produce biomedical product to control microbial population of infection or diseases causing by Fusobacterium nucleatum.In this study these antimicrobial effective silver nanoparticle were synthesized by using apple peel, therefore this technic can be replace chemical and physical method of nanoparticle

Silver nanoparticles, Periodontitis, Fusobacterium nucleatum, UV- spectroscopy, IR spectroscopy

"Biosynthesis of Silver nano Particles from Aqueous Extract of Apple Peel and Its Antimicrobial Activity Against Fusobacterium nucleatum", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.24-29, April-2019, Available :http://www.jetir.org/papers/JETIR1904404.pdf

"Biosynthesis of Silver nano Particles from Aqueous Extract of Apple Peel and Its Antimicrobial Activity Against Fusobacterium nucleatum", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp24-29, April-2019, Available at : http://www.jetir.org/papers/JETIR1904404.pdf