• T. Sujeshwari
• E. Akila
• P. Maheswaran

The aim of the present work was to synthesize the Schiff base ligand and its Copper(II) metal complex from the condensation of o-phthalaldehyde and p-nitroaniline. The synthesized Schiff base and its metal complex were characterized by elemental analysis, FTIR, 1HNMR and UV spectral studies. Results: The study reveals that the Schiff base ligand implicated the N4 donor atom. On the basis of spectral data, distorted octahedral geometry is proposed for the Cu(II) complex. The Schiff base and its metal complex were screened for their antibacterial, antioxidant and DNA cleavage activities. Conclusion: The Cu(II) complex exhibited good antimicrobial activity when compared to the free ligand.

Schiff base, antibacterial, antioxidant activities and DNA cleavage

"DNA CLEAVAGE, ANTIOXIDANT AND ANTIBACTERIAL STUDIES OF COPPER(II) COMPLEX DERIVED FROM N, N'-(1, 2 PHENYLENEBIS(METHANYLYLIDENE)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.22-31, April-2019, Available :http://www.jetir.org/papers/JETIR1904504.pdf

"DNA CLEAVAGE, ANTIOXIDANT AND ANTIBACTERIAL STUDIES OF COPPER(II) COMPLEX DERIVED FROM N, N'-(1, 2 PHENYLENEBIS(METHANYLYLIDENE)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp22-31, April-2019, Available at : http://www.jetir.org/papers/JETIR1904504.pdf