• Dr. Mayuri Dholaria
• Dr. Piyush Desai

UTI is one of the serious health problem throughout the world and development of antibiotic resistance is a worldwide problem that has led to the need for development of novel antimicrobials and use of natural products which is safe and effective. Bioactive compounds of Medicinal plants have proven to be a potential and effective cure against many diseases since centuries. The objective of this study is to analyze phytoconstituents and antibacterial property of ethanol extract of Boerhaavia diffusa whole plant against multi-drug resistant UTI pathogens isolated from urine samples collected from patients suffering from UTI. Antimicrobial susceptibility test of 515 urinary isolates against 12 different antibiotics was performed to select multi drug resistant bacterial species and 7 different highly resistant bacterial species were selected for this study. Preliminary phytochemical analysis and in-vitro antibacterial activity was screened by well diffusion method against selected MDR bacterial species. MIC values were also determined to find minimum effective concentration. The ethanol extract showed good antibacterial activity against all selected MDR uropathogens. Qualitative phytochemical test showed presence of alkaloid, tannin, terpenoids and cardiac glycosides. Results of the present study showed that B. diffusa can be used as a potential source for drug development for the treatment of Urinary Tract Infection caused by multi drug resistant bacteria.

UTI, Antibacterial activity, Phytochemical analysis, Boerhaavia diffusa, MIC

"Phytochemical Screening and Antibacterial Effect of Boerhaavia diffusa ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.77-83, April-2019, Available :http://www.jetir.org/papers/JETIR1904511.pdf

"Phytochemical Screening and Antibacterial Effect of Boerhaavia diffusa ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp77-83, April-2019, Available at : http://www.jetir.org/papers/JETIR1904511.pdf