• Shalini, B.U.
• Sushmitha, R.

Acne is a skin disease which causes painful social and psychological effects on sufferers. It is a problem for many adults as well as for many teenagers. The primary factors involved in the formation of acne lesions are increased sebum production, sloughing of keratinocytes, bacterial growth and inflammation. Propionibacterium acnes (P. acnes), an anaerobic pathogen, plays an important role in the pathogenesis of acne. The excessive use of antibiotics for long periods leads to increased resistance in acne causing bacteria. To overcome the problem of antibiotic resistance, essentials oils and medicinal plant extracts have been extensively studied as an alternative. In the present study, 13 common oils were investigated for their anti-acne potential against Propionibacterium acnes and antioxidant activity. Antibacterial activity was investigated using well diffusion method. Among the oils investigated for antibacterial activity, Lemongrass oil showed the maximum zone of inhibition followed by Lemon oil. The least antibacterial activity was exhibited by Calamus oil. The free radical scavenging activity was estimated by 1, 1-Diphenyl-2-picryl-hydraxyl (DPPH) assay. Lemongrass oil showed the highest antioxidant activity and least was shown by Jojoba oil. There was a good correlation between the oils showing antioxidant activity and anti-acne activity. The oils which exhibited highest inhibitory effect against Propionibacterium acnes and anti-oxidant activity in the present study can be incorporated into the cosmetic formulation and can be used to treat acne.

antioxidant, antiacne, Propionibacterium, oil, acne

"EVALUATION OF SOME SELECTED OILS FOR THEIR ANTIOXIDANT ACTIVITY AND ANTI-MICROBIAL POTENTIAL AGAINST ACNE CAUSING BACTERIUM PROPIONIBACTERIUM ACNE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.539-549, April-2019, Available :http://www.jetir.org/papers/JETIR1904583.pdf

"EVALUATION OF SOME SELECTED OILS FOR THEIR ANTIOXIDANT ACTIVITY AND ANTI-MICROBIAL POTENTIAL AGAINST ACNE CAUSING BACTERIUM PROPIONIBACTERIUM ACNE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp539-549, April-2019, Available at : http://www.jetir.org/papers/JETIR1904583.pdf