• Dr Seema Mishra

Abstract: Acute lower respiratory infection (ALRTI) is the leading cause of death in children below five years of age. Identification of modifiable risk factors of severe ALRTI may help in reducing the burden of disease. A hospital based case control & placebo study was undertaken to determine the effect of Zinc supplementation in ARI affected children up to five to twelve years. A case definition of severe ARI as given by World Health Organization (WHO) was used for cases. Lack of breast-feeding, upper respiratory infection in mother, upper respiratory infection in siblings, severe malnutrition, cooking fuel other than liquid petroleum gas, inappropriate immunization for age and history of LRI in the family were the significant risk factors associated with ARI. The affected children were divided in three groups ,15 demographically matched children in each group –the 1st group was intervention group ,supplemented with Zinc in the form of Zevit for about 3 months , the second group was control group and the 3rd group was placebo group .Before intervention the relevant parameters were estimated in all subjects and after intervention the parameters were analyzed and it was found that the Zn supplemented group had significant improvement in Spirometry and PEFR results also the level of lung infections was low . The blood parameters showed better corrected results after Zn supplementation.

Key words: Acute Respiratory Infections, PEFR, Mucus Plug, Spirometry, PEFR, Zevit .

"Effect of zinc supplementation on ARI in children with cystic fibrosis & Pneumonia ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 2, page no.142-150, February 2019, Available :http://www.jetir.org/papers/JETIR1904822.pdf

"Effect of zinc supplementation on ARI in children with cystic fibrosis & Pneumonia ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 2, page no. pp142-150, February 2019, Available at : http://www.jetir.org/papers/JETIR1904822.pdf