• S SHOBHA RANI
• KAMSANI SRAVANI

Glipizide is An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.Glipizide is a anti-diabetic medicine which is used to type 2 diabetics.The effectiveness of Glipizide extended-release tablets in type 2 diabetes at doses from 5–60 mg once daily has been evaluated in 4 therapeutic clinical trials each with long-term open extensions involving a total of 598 patients. Once daily administration of 5, 10 and 20 mg produced statistically significant reductions from placebo in hemoglobin A1C, fasting plasma glucose and postprandial glucose in patients with mild to severe type 2 diabetes.

Gastroretensive. Glipizide ,Optimized , polymers

"FOMULATION AND EVALUATION OF GASTRORETENTIVE MUCOADHESIVE SUSTAINED RELEASE OF GLIPIZIDE TABLETS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.380-402, April-2019, Available :http://www.jetir.org/papers/JETIR1904858.pdf

"FOMULATION AND EVALUATION OF GASTRORETENTIVE MUCOADHESIVE SUSTAINED RELEASE OF GLIPIZIDE TABLETS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp380-402, April-2019, Available at : http://www.jetir.org/papers/JETIR1904858.pdf