• Gautam Tomar
• Meenakshi Bhatt

Water is known as the "elixir of life": in the pharmaceutical industry, water quality is an essential and priority ingredient of various pharmaceutical preparations and is also used to clean process equipment and, therefore, performs a fundamental role in the pharmaceutical industry: it is the most used raw material in the production of active pharmaceutical ingredients (API), in intermediate products, in the finished dosage forms, making it an important raw material in GMP and in the validation of the manufacturing process. The objective of purifying and validating water is to demonstrate that the process, when operating within certain limits, produces the product with a high degree of guarantee of consistency and specified quality. To achieve high quality, the purity and security of water system validation is essential. The validation process not only provides high quality water, but also provides a standard framework for monitoring the safety, effectiveness and outcome of the process. The purpose of this discussion is an attempt to look at the various aspects of purification and validation that include components of water treatment systems, equipment qualification, different qualification stages, documentation, validation, preventive maintenance, change control and post- monitoring.

Validation; API; Water treatment systems.

"Water Purification and Validation System in Pharmaceuticals", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.478-491, April-2019, Available :http://www.jetir.org/papers/JETIR1904J63.pdf

"Water Purification and Validation System in Pharmaceuticals", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp478-491, April-2019, Available at : http://www.jetir.org/papers/JETIR1904J63.pdf