• Poonam Ahlawat
• Dr. Navita Rani

This paper reports regulation of endoglucanase (EC 3.2.1.4) and xylanase (EC 3.2.1.8) production in submerged cultivation of four white-rot basidiomycetes. Among carbon sources tested, the Avicel-based medium provided the highest levels of both hydrolases activities in all fungal cultures. Dialysed culture filtrates, after growth on cellobiose, wese also effective in degrading crystalline cellulose (Avicel). Cellulase, measured viscometrically with carboxymethylcellulose as substrate and therefore referred to as C M-cellulase, was induced by cellulose, glucomannan, cellobiose and, to a limited extent, by laminaribiose and cellobionic acid. Low CM-cellulase activities were also detectable when the organism was grown on other carbon sources. In culture media supplemented with readily metabolized non-inducing substrates, such as glucose, CM-cellulase activity did not increase after their exhaustion indicating that no derepression of constitutive CM-cellulase occurred. The use of glucose analogues gave some indications that cellobiose did not compete with glucose for the same transport carrier and that glucose catabolism was a prerequisite for the inhibition of CM-cellulase synthesis.

Induction, Catabolite Suppression, Cellobionic acid, CM-cellulase synthesis, Fungal Cellulase Synthesis

"INDUCTION AND CATABOLITE SUPPRESSION IN THERMOPHILIC FUNGAL CELLULASE SYNTHESIS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 4, page no.548-558, April-2019, Available :http://www.jetir.org/papers/JETIR1904T73.pdf

"INDUCTION AND CATABOLITE SUPPRESSION IN THERMOPHILIC FUNGAL CELLULASE SYNTHESIS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 4, page no. pp548-558, April-2019, Available at : http://www.jetir.org/papers/JETIR1904T73.pdf