• Dr. S. L. Prakash
• Prof. Dr. M. Thiruthani

Siddha medicine is one of the oldest and the foremost of all other medical systems of the world. In Siddha, Mercurial compounds namely PANCHASOOTHAM are widely used to cure complicated and chronic disease. Pooram is one among the five compounds. Pooram is called as MERCUROUS CHLORIDE (CALOMEL),and it is identified and indicated for the treatment of many diseases in ancient Siddha medicine. One of the most important aspects of siddha medicine is purification of raw materials before using them for medicine. The objective of the present study is to evaluate the Physico-Chemical analysis of Siddha raw drug POORAM before and after purification i.e. quantitative parameters such as pH, ASH (%w/w), ACID INSOLUBLE ASH (%w/w), LOSS ON DRYING @1050C, WATER SOLUBLE EXTRACTIVE, ALCOHOL SOLUBLE EXTRACTIVE, are tested is carried out in the present study. Qualitative analysis of the formulation showed the presence of elements of CHLORIDE and SULPHATE in both forms and presence of MERCURY and AMINO ACIDS in raw pooram and these are absent in purified forms. In this research revealed the physicochemical changes in purification procedures of Siddha drugs. Hence further quantitative chemical & Electro chemical research needed for scientific evidence to prove why Siddhars’ give importance to purification for herbo-mineral Drugs.

Pooram - Mercurous Chloride, Panchasootham, Siddha Medicine

"Physico-Chemical Analysis of Siddha Drug POORAM- A comparative Evaluation between before and after purification of raw drug", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.196-200, May-2019, Available :http://www.jetir.org/papers/JETIR1905632.pdf

"Physico-Chemical Analysis of Siddha Drug POORAM- A comparative Evaluation between before and after purification of raw drug", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp196-200, May-2019, Available at : http://www.jetir.org/papers/JETIR1905632.pdf