• D.Gandhiraj
• Wesely E.G
• Palanisamy A
• Sahanapriya.s

The genera Staphylococcus are normally present in normal skin or nasal colonizers of human beings. Conventionally the Staphylococcus is divided into two groups on the basis of the coagulase reaction. The coagulase-positive staphylococci is the most commonly isolated pathogenic species S aureus . The coagulase-negative staphylococci (CONS) are now known to comprise over 38 species. The CONS are common commensals of skin, although some species can cause oppartunisitic infections. . Methicillin resistance is indicative of multiple resistance. Methicillin-resistant S aureus (MRSA) causes outbreaks in hospitals among surgical patients and also now isolated from the community as well. Methicillin-resistant Staphylococcus aureus (MRSA) by definition harbors a gene, mecA, for methicillin resistance. The mecA gene codes for penicillin binding protein (PBP) 2a which allows MRSA to continually synthesize its cell wall in the presence of β-lactam antibiotics.Laboratory diagnosis and susceptibility testing are crucial steps in treating and preventing MRSA infections. Therefore, methods used to detect MRSA in clinical samples should have high sensitivity and specificity and, most importantly, the result should be available within a short period of time. The study have used various methods have evolved for rapid detection of methicillin-resistant staphylococcus aureus .

Staphylococcus Aureus, MRSA, mecA

"EFFICACY OF LABORATORY TESTS TO DIAGNOSE MRSA: A MULTI-CENTRE STUDY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.462-466, May-2019, Available :http://www.jetir.org/papers/JETIR1905961.pdf

"EFFICACY OF LABORATORY TESTS TO DIAGNOSE MRSA: A MULTI-CENTRE STUDY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp462-466, May-2019, Available at : http://www.jetir.org/papers/JETIR1905961.pdf