• Jameel Ahemad Mohammad Abbas
• Dr.Sumer Singh
• Dr.Majaz Quazi
• Ansari Yaasir Ahmed
• Ansari Mohd.Razi

The most common preferred route is oral rout of administration. Today oro-dispersible tablet from novel drug delivery system gain importance from patient. Which is administer to the patient to control the attack of angina or hypertension, but for immediate control, Oro-dispersible tablet is oral solid dosage form in which the tablet gets dispersed in oral cavity in absence of water. Various manufacture are formulated this formulation by various method. The most importance thing in this formulation are masking of taste of drugs. Generally oro-dispersible tablet are prepared by direct compression method. Dry granulation, wet granulation, Spry drying is the various methods for preparation of oro-dispersible tablet. Oro-dispersible tablet generally contains filler, glidant, anti-adherent super disintegrate, sweetener and resins. Evaluation parameter includes hardness, friability, wetting time, moisture uptake, disintegration test, and dissolution test. Wetting time, Disintegration time, and Dissolution test is directly proportional to the hydrophobic ingredient added for lubrication, anti-adherent, Glidant action. These hydrophobic ingredient are Magnesium Stearate. To oppose the action of magnesium stearate, hydrophilic additives are incorporated viz Sodium lauryl sulphate.

Oro-dispersible tablet, wetting time, Dissolution test

"Formulation and Evaluation of Orodispersible tablets of Nifedipine 10 mg", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.248-255, May-2019, Available :http://www.jetir.org/papers/JETIR1905G36.pdf

"Formulation and Evaluation of Orodispersible tablets of Nifedipine 10 mg", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp248-255, May-2019, Available at : http://www.jetir.org/papers/JETIR1905G36.pdf