• Shashi bala Prabhakar
• Dr.Swati Khare
• Dr.Ritu Thakur Bais

The objective of this study is to compare the antimicrobial activity of the essential oil from bark of Cinnamomum zeylanicum and fruit of Myristica fragrans (Houtt). The essential oil was extracted from fruit peels by steam distillation using Clevenger’s type apparatus. The essential oil of Cinnamomum zeylanicum and Myristica fragrans was analysed by GC-MS and their antimicrobial and antioxidant activity were tested. In vitro antioxidant activity as assessed by 2, 2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, Superoxide assay and Reducing power assay. Their antimicrobial activity is tested against four strains of bacteria Escherichia coli, Streptococcus bacillus, Proteus vulgaris and Staphylococcus aureus Efficacy of the essential oil of Cinnamomum zeylanicum and Myristica fragrans was compared using Well Diffusion method. Ampicillin and Amphotericin-B, an anitibiotic, is used as a positive control. According to the results of the minimal inhibitory concentration (MIC) we can conclude that the essential oil of both the plant Cinnamomum zeylanicum and Myristica fragrans has antimicrobial potential against all microorganisms studied. The essential oil of Cinnamomum zeylanicum showed strong antimicrobial activity against E.coli. However, the essential oil of Myristica fragrans was found to have more effective antimicrobial activity showing its maximum efficacy for S.aureus. Present study concludes that essential oil from Cinnamomum zeylanicum and Myristica fragrans have potent antioxidant role and also have a broad spectrum antibacterial activity against human pathogens. Keywords: Cinnamomum zeylanicum, Myristica fragrans, 2, 2'-diphenyl-1-picrylhydrazyl

Cinnamomum zeylanicum, Myristica fragrans, 2, 2'-diphenyl-1-picrylhydrazyl

"Comparative analysis of antioxidant, antimicrobial and analytical profile of essential oils extracted from Cinnamomum zeylanicum (Blume) bark and Myristica fragrans (Houtt) fruit.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.399-414, May-2019, Available :http://www.jetir.org/papers/JETIR1905O64.pdf

"Comparative analysis of antioxidant, antimicrobial and analytical profile of essential oils extracted from Cinnamomum zeylanicum (Blume) bark and Myristica fragrans (Houtt) fruit.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp399-414, May-2019, Available at : http://www.jetir.org/papers/JETIR1905O64.pdf