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June-2019
eISSN: 2349-5162
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Journal of Emerging Technologies and Innovative Research ( An International Scholarly Open Access Journal, Peer-reviewed, Refereed Journal )
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UGC Approved Journal no 63975(19)
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UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975
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Published Paper ID:
JETIR1906236
Registration ID:
213949
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Title
STABILITY INDICATING ASSAY METHOD DEVELOPMENT AND VALIDATION OF ACLIDINIUM BROMIDE AND FORMOTEROL FUMARATE BY RP-HPLC
Authors
Abstract
A validated stability indicating RP-HPLC method for Aclidinium Bromide and Formoterol fumarate was developed by separating its degradation products on a C18 (150x4.6mm, 3.5µm) waters symmetry column using 1ml Tri Ethyl Amine of pH=7.0 adjusted with Ortho Phosphoric acid and acetonitrile in simple isocratic at a flow rate of 1.0 ml/min. The column effluents were monitored by a photodiode array detector set at 264nm. The method was validated in terms of specificity, linearity, accuracy, precision, detection limit, quantification limit and robustness. The proposed method is validated as per ICH Q2 (R1) guidelines.
Key Words
Aclidinium Bromide and Formoterol fumarate, RP-HPLC
Cite This Article
"STABILITY INDICATING ASSAY METHOD DEVELOPMENT AND VALIDATION OF ACLIDINIUM BROMIDE AND FORMOTEROL FUMARATE BY RP-HPLC", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.625-629, June-2019, Available :http://www.jetir.org/papers/JETIR1906236.pdf
ISSN
2349-5162 | Impact Factor 7.95 Calculate by Google Scholar
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Cite This Article
"STABILITY INDICATING ASSAY METHOD DEVELOPMENT AND VALIDATION OF ACLIDINIUM BROMIDE AND FORMOTEROL FUMARATE BY RP-HPLC", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp625-629, June-2019, Available at : http://www.jetir.org/papers/JETIR1906236.pdf
Publication Details
Published Paper ID: JETIR1906236
Registration ID: 213949
Published In: Volume 6 | Issue 6 | Year June-2019
Page No: 625-629
Country: Vijayawada, Andhra Pradesh, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIR1906236
Published Paper PDF: https://www.jetir.org/papers/JETIR1906236
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