• Mrunal Vaidya
• Swati Kolhe
• Sachin Tembhurne

In this study, we tested the effect of hydroalcoholic extract of Dalbergia sissoo on female sexual dysfunction (FSD) in 30 days postsurgical bilateral ovariectomized female rats. 3-month old female Wistar rats were used and distributed in 5 groups, ovariectomized (Ovx) groups with 30 days, Ovx treated hydroalcoholic extract of Dalbergia sissoo (200 & 400 mg/kg), Ovx treated with standard β Estradiol (0.1mg/kg/s.c) and estrous control rats. All treatments were given for further 28 days after post-surgical period (30 days) in ovariectomized female rats. They were evaluated on the 14th day and on 28th day in the copulatory arena with the sexually experienced male rats and for serum estrogen levels. After 28 days of treatment, histopathology of uterus and vagina were quantified. The treatment of the hydroalcoholic extract of Dalbergia sissoo (200 and 400 mg/kg) in the Ovx rats shows significance increase in the sexual activity, lordosis, serum estrogen level and histology results. All the results of Dalbergia sissoo are comparable with standard β Estradiol. Results suggest that 28 days of treatment with hydroalcoholic extract of Dalbergia sissoo is able to increase the sexual function in estrogen deficient females, serum estrogen levels and decreased atrophy of vaginal epithelium and uterus.

Dalbergia sissoo, Post menopause, Copulatory arena, Serum estrogen level, Histopathology, Atrophy.

"PRECLINICAL EVALUATION OF ETHANOLIC EXTRACT OF DALBERGIA SISSOO FOR FEMALE SEXUAL DYSFUNCTION IN EXPERIMENTAL RATS. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.400-411, June-2019, Available :http://www.jetir.org/papers/JETIR1906348.pdf

"PRECLINICAL EVALUATION OF ETHANOLIC EXTRACT OF DALBERGIA SISSOO FOR FEMALE SEXUAL DYSFUNCTION IN EXPERIMENTAL RATS. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp400-411, June-2019, Available at : http://www.jetir.org/papers/JETIR1906348.pdf