UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 6 Issue 6
June-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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JETIR1906588


Registration ID:
214578

Page Number

29-34

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Title

SYNTHESIS & BIOLOGICAL EVALUATION OF OXADIAZOLE TETHERED TETRAHYDROTHIENOPYRIDINES

Abstract

Oxadiazoles were good bioioster of treasured functional groups in medicinal chemistry such as esters. Considering this, synthesis of oxadiazole at active position of tetrahydrothienopyridine was magnificently accomplished. Novel series of Tetrahydrothienopyridine oxadiazole hybrids were synthesized by condensation of acid and hydrazide followed cyclization using tosyl chloride and N-substitutions was achieved by EDC.HCl as a peptide coupling reagent using different types of acids. All analogs have been characterized by 1H NMR, IR and Mass. In-vitro inhibition of % platelet aggregation was screened on human blood and found encouragingly some analogs to be effective.

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"SYNTHESIS & BIOLOGICAL EVALUATION OF OXADIAZOLE TETHERED TETRAHYDROTHIENOPYRIDINES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.29-34, June-2019, Available :http://www.jetir.org/papers/JETIR1906588.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"SYNTHESIS & BIOLOGICAL EVALUATION OF OXADIAZOLE TETHERED TETRAHYDROTHIENOPYRIDINES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp29-34, June-2019, Available at : http://www.jetir.org/papers/JETIR1906588.pdf

Publication Details

Published Paper ID: JETIR1906588
Registration ID: 214578
Published In: Volume 6 | Issue 6 | Year June-2019
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.21418
Page No: 29-34
Country: pune, Maharashtra, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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