• SUNITHA R MANGALA
• SHIVAPRASAD K HALAPPA
• VIRUPAXAPPA S BETEGERI
• LATHA M
• SHIVASHANKAR

A modest and sensitive method for the determination of trimethoprim has been suggested in pure and pharmaceutical formulations. The method is based on the reaction of trimethoprim with alkaline KMnO4 which leads to the formation of a green coloured complex having a λmax at 520nm. The system obeyed Beer’s law and the Sandell’s sensitivity. The preferred method was successfully applied to direct the elected trimethoprim with high precision and accuracy compared to standard method as revealed by t-values and F-values.

Trimethoprim, Alkaline Potassium permanganate, Spectrophotometery

"A NEW SENSITIVE SPECTROPHOTOMETRIC METHOD FOR THE ASSAY OF TRIMETHOPRIM USING ALKALINE POTASSIUM PERMANGANATE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.300-303, June-2019, Available :http://www.jetir.org/papers/JETIR1906B45.pdf

"A NEW SENSITIVE SPECTROPHOTOMETRIC METHOD FOR THE ASSAY OF TRIMETHOPRIM USING ALKALINE POTASSIUM PERMANGANATE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp300-303, June-2019, Available at : http://www.jetir.org/papers/JETIR1906B45.pdf