• Dr. Shriti Agrawal
• Dr. Harish Bhakuni
• Prof. Ram Kishor Joshi

Acromegaly is a rare disease caused due to hypersecretion of Growth Hormone and consequently of Insulin-like Growth Factor-I (IGF-1) caused by Pitutary Microadenoma or Macroadenoma. The Growth Hormone and IGF-1 play a role in the regulation of bone metabolism. Among musculoskeletal symptoms the most prevalent is Arthropathy, it may be present as the earliest clinical symptom of the disease and the most commonly involved joints are hips, shoulders, knees, hands, and elbows. According to Ayurvedic classics Acromegaly induced Arthropathy can be correlated with sandhivata as in this disease vitiation of vata and so vitiation in asthi and sandhi occurs results in pain and inflammation in spinal region and bilateral knee joints as both are the most commonly involved areas. The present case study was dealt with, keeping in mind to prevent the development of irreversible complications of the disease and improve the quality of life in patients suffering from the disease. In this case an effort was made to treat a 65 years old male patient known case of acromegaly having pain in low back region and bilateral knee joints since two and half years treated with shiva gutika having ingredients like shilajatu dashmoola, guduchi, bala, trikatu etc. in 3gm in BD dose with 40 ml of pathyadi kwatha as anupana for 6 months. It has property of anti-inflammation, reduction of pain, deepana, ama pachana and thus breaking the pathogenesis of disease and strengthening the roga ashaya. It showed relief in sign and symptoms of the Acromegaly induced Arthropathy in patient without any side effect / adverse effects during the course of treatment.

Acromegaly induced Arthropathy, Growth hormone, Insulin-like growth factor-I, Pitutary adenoma , Shiva gutika, Pathyadi kwatha.

"Ayurvedic Management of Acromegaly induced Arthropathy - A Case Study", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.862-866, June 2019, Available :http://www.jetir.org/papers/JETIR1906N33.pdf

"Ayurvedic Management of Acromegaly induced Arthropathy - A Case Study", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp862-866, June 2019, Available at : http://www.jetir.org/papers/JETIR1906N33.pdf