• Helisha Ruth Obonyo
• Dr.V.Senthemarai selvi

The aim of present study was to evaluate the significance of Phaseolus vulgaris L seed extract for anti-arthritic activity using in vitro inhibition of protein denaturation model and anti-inflammatory activity by HRBC (Human Red Blood Cell) membrane stabilization method assay whereby Diclofenac sodium was used as a standard drug for comparisation. Ant-arthritic activity was carried out using 250-1000 µg/ml concentration, whereas anti-inflammatory activity at the concentration of 250- 1000 µg/ml. The results of the present study represents that the aqueous seed extract of Phaseolus vulgaris L demonstrates dose dependent inhibition. The maximum ant-arthritic activity of Phaseolus vulgaris L was found at the concentration of 1000 µg/ml with 80.66% inhibition. Correspondingly maximum anti-inflammatory activity of Phaseolus vulgaris L was observed at the concentration of 1000 µg/ml with 93.06% inhibition. It is apparent that the cause of inflammation and arthritis is mainly due to denaturation of tissue proteins and the present study explains that denaturation of proteins is inhibited, inhibiting the progression of arthritis and reducing the cause of inflammation.

Phaseolus vulgaris L; anti-inflammatory; anti-arthritic; HRBC

"Evaluation of In vitro Anti-Inflammatory and Anti-arthritic activity of Phaseolus vulgaris L Aqueous extract", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.914-919, June 2019, Available :http://www.jetir.org/papers/JETIR1906U23.pdf

"Evaluation of In vitro Anti-Inflammatory and Anti-arthritic activity of Phaseolus vulgaris L Aqueous extract", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp914-919, June 2019, Available at : http://www.jetir.org/papers/JETIR1906U23.pdf