• Dr Deepika
• Dr Ashish Kumar Malik
• Dr Kiran Dahiya
• Dr Veena Singh Ghalaut

Abstract: Introduction: Menopause is cessation of menstrual flow and is defined as one year without menses. The age at which menopause occurs is genetically defined and is around 51 years on an average. The ovaries start to lose their estrogen producing capacity in the late thirties which is completed by mid-fifties. This phenomenon is known as the menopausal transition. There is progressive loss of estrogen, which is responsible for vasomotor disturbances as well as weight problems among postmenopausal women. The BMI in postmenopausal females is considered as a factor of diminishing reproductive hormones. So, a correlation of BMI and serum nitric oxide in north Indian post-menopausal hypothyroid females may provide us with a probable link between BMI and nitric oxide levels in determining the causes of deterioration of cardiovascular health in postmenopausal women. Methods: This study was conducted in the Department of Biochemistry in collaboration with Department of Medicine and Department of Obstetrics and Gynecology, Pt. B. D. Sharma. A total of 30 apparently healthy postmenopausal women were enrolled. Nitric oxide was estimated by griess reagent and for routine biochemistry we used Randox Suzuka autoanalyzer. Results: The mean BMI of post-menopausal women was found be on higher side with a mean of 29.03±3.56. The mean NO levels were 33.67±5.17. We observed a positive correlation between BMI and serum NO levels. Conclusion: The study found that there is a link between the body fat and the synthesis of nitric oxide which may be a compensatory mechanism for the obese people. Clinicians while observing nitric oxide levels should keep in mind the BMI status of the patient.

Nitric oxide, Menopause, Estrogen, BMI

"IS NITRIC OXIDE RELATED TO BMI IN POST-MENOPAUSAL FEMALES?", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.936-939, June 2019, Available :http://www.jetir.org/papers/JETIR1906Y56.pdf

"IS NITRIC OXIDE RELATED TO BMI IN POST-MENOPAUSAL FEMALES?", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp936-939, June 2019, Available at : http://www.jetir.org/papers/JETIR1906Y56.pdf