• Vijya Shree
• Dr.(Mrs.)Farida Bano

Abstract Agriculture productivity was increased in last few decay due to increase in population. Pesticides are widely applied on these crops for their protection. Chlorpyrifos is moderately toxic to humans and chronic exposure has been linked to neurological effects and developmental disorders. Asparagus racemosus is a used for prevent ageing, increase longevity, impart immunity, improve mental function, nervous disorders, dyspepsia, tumors, inflammation, neuropathy and hepatopathy. Thus the present study is designed to find effect of Asparagus racemosus on free oxygen radical and male fertility restoration against pesticide exposed infertility. The ‘treatment’ groups received chloropyrifos 10 mg/kg b.w by gavage method for four weeks for preparation of infertility model. Asparagus racemosus (400 mg/kg/b. w/day) administered to chloropyrifos exposed group for eight weeks. Serum was collected for antioxidant study and semen for sperm count. Sodium dismutase, catalase, lipid peroxidation and sperm count were decreased many fold in pesticide administered group. While Asparagus racemosus shows effective restoration in sodium dismutase, catalase and lipid peroxidation. Sperm count was almost normal after Aspergilus treatment for eight weeks. It is concluded from study that Asparagus racemosus causes restoration in free oxygen radical including catalase and sodium dismutase. It also restores lipid per oxidation to normal limit. Asparagus racemosus causes effective restoration in sperm count and maintains normal fertility in male.

Key Word: Pesticide, Fertility, Free oxygen radical, Catalase, Sperm

"Restorative effect of Asparagus racemosus on male fertility through antioxidant enzymes in rat", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 1, page no.191-197, January 2019, Available :http://www.jetir.org/papers/JETIR1906Y98.pdf

"Restorative effect of Asparagus racemosus on male fertility through antioxidant enzymes in rat", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 1, page no. pp191-197, January 2019, Available at : http://www.jetir.org/papers/JETIR1906Y98.pdf