• Himabindu
• Azra afroz
• Meena Kumari
• Harita Shyam
• Swetha sri

Mrs. Meena kumari, HOD – Department of nutrition, Mrs. Harita Shyam, Chief dietitian, Apollo Hospitals, Mrs. Swetha sri, Senior dietician, Apollo Hospitals C. Hima bindu, Azra afroz AIM: The aim of the study is to compare whole-protein formula (WPF) and a peptide - based formula (PEF) in terms of tolerance and nutritional outcomes in Critically ill patients. OBJECTIVE: To observe the effect of WPF and SEF with specific outcomes of GI tolerance, length of stay of the patient and calorie deficit. METHODOLOGY: A Observational study was performed in a Multi speciality hospital to assess the differences between WPF and PEF in critically ill patients in ICU’S with a sample size of 20(10 on standard supplements,10 on Peptide based formula) for a period of 2 months. The selection criteria included critically ill patients ,who remained in ICU for more than 72 hours, with age >18yrs and patients on RT feeds. Detailed data was collected prospectively and assessment of nutritional status (Anthropometric measurements, Biochemical parameters) was done using a pretested questionnaire to collect the day to day data of the study group. Statistical analysis was done in which percentages were calculated for some parameters( Gender, BMI, Tolerance, GI symptoms) & Student t-test was done for Total length of stay, Length of stay on ventilator, Length of stay in ICU, SOFA score, Albumin, Prealbumin, Planned calories, Received calories, Calorie deficit, Received protein, Protein deficit. RESULTS: The results obtained illustrated that the patients of both the groups showed good tolerance towards the feed given, but 20% of the patients belonging SEF group showed diarrhea and patients belonging WPF group showed no symptoms of diarrhea. Length of stay on ventilator and in the ICU was more in patients belonging to WPF group when compared to SEF group though it was observed statistically insignificant (P-Value > 0.05) where as total length of stay in the hospital was more in patients belonging to WPF group when compared to SEF group which was observed statistically significant with P-Value 0.001 (P-Value <0.05) when T-test was performed. Calorie & protein deficit was observed in both WPF and SEF groups due to feed disturbances. CONCLUSION: Based on the results, it can be concluded that no significant difference was observed between both the groups except for the length of stay on ventilator , ICU length of stay, though it was observed statistically insignificant and total length of stay in hospital which was less in SEF when compared to WPF formula which was observed statistically significant.

WPF,SEF,total length of stay,length of stay on ventilator,length of stay in ICU,tolerance,calorie and protein deficit,Student t-test.

"An observational comparative study of critically ill patients on standard formula and peptide based formula.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.1081-1095, June 2019, Available :http://www.jetir.org/papers/JETIR1907296.pdf

"An observational comparative study of critically ill patients on standard formula and peptide based formula.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp1081-1095, June 2019, Available at : http://www.jetir.org/papers/JETIR1907296.pdf