• Sumathi R 1
• 1 Sarala E 2

Abstract: In this study, different concentrations of the methanolic extract of leaves of the plant Ocimum basilicum L was subjected to in-vitro cytotoxic activity study against MCF-7cells using the MTT assay. Percentage cell viability of cell lines were carried out by using Trypan blue dye exclusion technique MTT assay was used to evaluate the reduction of viability of cell cultures in the presence and absence of the extract. Cell viability was inhibited to different extents by different concentrations of the extract. Phytochemical analysis showed the presence of alkaloids, tannins, flavonoids, terpenoids, phenols and saponins.

Keywords: Cytotoxic activity, MCF-7 cell line, MTT assay, Ocimum basilicum L, phytochemicals

"INVITRO ANTI BREAST CANCER ACTIVITY OF METHANOLIC EXTRACT OF Ocimum basilicum L leaves AGAINST MCF-7 Cell Line", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.1041-1046, June 2019, Available :http://www.jetir.org/papers/JETIR1907451.pdf

"INVITRO ANTI BREAST CANCER ACTIVITY OF METHANOLIC EXTRACT OF Ocimum basilicum L leaves AGAINST MCF-7 Cell Line", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp1041-1046, June 2019, Available at : http://www.jetir.org/papers/JETIR1907451.pdf