• D. Jim Livingston
• C. Joel
• R. Biju Bennie
• Thayalaraj Christopher Jeyakumar
• C. D. Sheela

Three mixed ligand copper(II) complexes of 3-formylchromone and 2-aminophenol based Schiff base ligand (L) and N,N-donor ligands viz., [Cu(L)(bpy)](L1),[Cu(L)(phen)](L2) and [Cu(L)(dmp)](L3),{Where bpy= 2,2’-bipyridine, phen = 1,10-phenanthroline, dmp = 2,9-dimethylphenanthroline} have been synthesized and characterized by 1H-NMR, UV-Vis , FT-IR, ESI-mass and EPR spectral studies. These complexes were found to bind with CT DNA which was explored using absorption and emission spectral titrations and has been revealed that they could bind to DNA via, a mode of intercalation. The difference in the relative emission intensities of DNA-bound ethidium bromide observed upon interaction with the complexes found to parallel the trend in DNA binding affinities.

3-formylchromone, Schiff base, Copper(II) complex, CT-DNA, Intercalation.

"Synthesis, Characterization andDNA binding affinities of mixed ligand Cu(II)complexes of 3-((E)-(2-hydroxyphenylimino)methyl)-4H-chromen-4-one ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.633-649, June 2019, Available :http://www.jetir.org/papers/JETIR1907688.pdf

"Synthesis, Characterization andDNA binding affinities of mixed ligand Cu(II)complexes of 3-((E)-(2-hydroxyphenylimino)methyl)-4H-chromen-4-one ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp633-649, June 2019, Available at : http://www.jetir.org/papers/JETIR1907688.pdf