• Jacintha Jasmine.D
• Paul Agastian

Antibiotic resistant pathogens are increasing at an alarming rate globally due to their sustainability to most commonly available antibiotics. Mining for novel antibiotics from unexplored habitats could pave way to combat the problem. Endophytic organisms are found to be beneficial sources of secondary metabolites which can be used against antibiotic resistant pathogens. The increasing demand for novel antibiotics led to the isolation of endophytic actinomycetes and fungi from the roots of Catharanthus roseus. The present study was carried out to screen the antimicrobial and anti fungal potentials of the ethyl acetate extracts of endophytic actinomycetes and fungi. Surface sterilization technique was performed and plating on starch casein agar for endophytic actinomycetes and water agar plates for endophytic fungi. Morphological, cultural and taxonomic properties for endophytic actinomycetes and fungi were studied. Antimicrobial studies showed that crude extracts of endophytic fungi showed high activity when compared to the ethyl acetate extracts of endophytic actinomycetes. In the case of anti fungal activity, using broth micro dilution method, actinomycetes extracts showed a minimum inhibitory activity.

Endophytic actinomycetes, endophytic fungi, antimicrobial activity, antifungal activity.

"ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF ENDOPHYTIC ACTINOMYCETES AND ENDOPHYTIC FUNGUS ISOLATED FROM THE ROOTS OF CATHARANTHUS ROSEUS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.438-455, June 2019, Available :http://www.jetir.org/papers/JETIR1907949.pdf

"ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF ENDOPHYTIC ACTINOMYCETES AND ENDOPHYTIC FUNGUS ISOLATED FROM THE ROOTS OF CATHARANTHUS ROSEUS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp438-455, June 2019, Available at : http://www.jetir.org/papers/JETIR1907949.pdf